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Genetics Faculty


Kristian Baker
Associate Professor
Department of Genetics
School of Medicine
Case Western Reserve University
Biomedical Research Building 629
2109 Adelbert Road
Cleveland, Ohio 44106-4955
Tel: (216) 368-0277
Fax: (216) 368-3432
E-mail: kristian.baker@case.edu


About Kristian Baker


Selected Publications

Presnyak V, Alhusaini N, Chen YH, Martin S, Morris N, Kline N, Olson S, Weinberg D, Baker KE, Graveley BR, Coller J (2015)
Codon optimality is a major determinant of mRNA stability.
Cell;160(6):1111-24
See PubMed abstract

Smith JE, Alvarez-Dominguez JR, Kline N, Huynh NJ, Geisler S, Hu W, Coller J, Baker KE (2014)
Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae.
Cell Rep;7(6):1858-66
See PubMed abstract

Geisler S, Lojek L, Khalil AM, Baker KE, Coller J (2012)
Decapping of long noncoding RNAs regulates inducible genes.
Mol Cell;45(3):279-91
See PubMed abstract

Baker KE, Nilsen TW (2011)
The Centrality of RNA, Then and Now
Cell;147: 962-963

Hu W, Petzold C, Coller J, Baker KE (2010)
Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae.
Nat Struct Mol Biol;17(2):244-7
See PubMed abstract

Hu W, Sweet TJ, Chamnongpol S, Baker KE, Coller J (2009)
Co-translational mRNA decay in Saccharomyces cerevisiae.
Nature;461(7261):225-9
See PubMed abstract

Meaux S, van Hoof A, Baker KE (2008)
Nonsense-mediated mRNA decay in yeast does not require PAB1 or a poly(A) tail.
Mol Cell;29(1):134-40
See PubMed abstract

Zaharik ML, Lamb SS, Baker KE, Krogan NJ, Neuhard J, Kelln RA (2007)
Mutations in yhiT enable utilization of exogenous pyrimidine intermediates in Salmonella enterica serovar Typhimurium.
Microbiology;153(Pt 8):2472-82
See PubMed abstract

Sweet TJ, Boyer B, Hu W, Baker KE, Coller J (2007)
Microtubule disruption stimulates P-body formation.
RNA;13(4):493-502
See PubMed abstract

Baker KE, Parker R (2006)
Conventional 3' end formation is not required for NMD substrate recognition in Saccharomyces cerevisiae.
RNA;12(8):1441-5
See PubMed abstract

Baker KE, Coller J (2006)
The many routes to regulating mRNA translation.
Genome Biol;7(12):332
See PubMed abstract

Baker KE, Condon C (2004)
Under the Tucson sun: a meeting in the desert on mRNA decay.
RNA;10(11):1680-91
See PubMed abstract

Baker KE, Coller J, Parker R (2004)
The yeast Apq12 protein affects nucleocytoplasmic mRNA transport.
RNA;10(9):1352-8
See PubMed abstract

Baker KE, Parker R (2004)
Nonsense-mediated mRNA decay: terminating erroneous gene expression.
Curr Opin Cell Biol;16(3):293-9
See PubMed abstract

Baker KE, Mackie GA (2003)
Ectopic RNase E sites promote bypass of 5'-end-dependent mRNA decay in Escherichia coli.
Mol Microbiol;47(1):75-88
See PubMed abstract

Baker KE, Ditullio KP, Neuhard J, Kelln RA (1996)
Utilization of orotate as a pyrimidine source by Salmonella typhimurium and Escherichia coli requires the dicarboxylate transport protein encoded by dctA.
J Bacteriol;178(24):7099-105
See PubMed abstract

Vial TC, Baker KE, Kelln RA (1993)
Dual control by purines and pyrimidines of the expression of the pyrD gene of Salmonella typhimurium.
FEMS Microbiol Lett;111(2-3):309-14
See PubMed abstract

Sørensen KI, Baker KE, Kelln RA, Neuhard J (1993)
Nucleotide pool-sensitive selection of the transcriptional start site in vivo at the Salmonella typhimurium pyrC and pyrD promoters.
J Bacteriol;175(13):4137-44
See PubMed abstract